We aim to design and fabricate nano-bio devices including diagnostic chips, DNA chips, and electronic devices. We focus on investigations of single-molecule imaging and electrical sensing of cellular signals to study basic physics and chemistry involved in biological systems. To develop the experimental platforms, we create micro/nanofluidic pores and channels by employing either semiconductor processes or 3D printing methods. By integrating single cell-level nano-bio devices, we offer customized bio-chips to explore fundamental biological systems and unveil genetics and biochemistry underlying the living organisms.

Wafer-scale fabrications of sub-20 nm nanopores and nanochannels for detecting single molecules in diagnostic devices

Ion transistors for manipulating DNA single molecules: Electrical trapping and stretching of DNA molecules

In-situ transmission electron microscopy (TEM) study of nanowires (NWs) and electronic memory devices